Mohamed Hosny Abdelnaby Hassan <br/><br/>
Elucidating the role of caveolae associated proteases in breast cancer Egyptian patients /  
 توضيح دور الانزيمات الخاصة بتكسير البروتينات والمرتبطة بكهوف الدهن (كافيولى) فى سرطان الثدى للمرضى المصريات  
Mohamed Hosny Abdelnaby Hassan ; Supervised Mona Mostafa Mohamed , Salwa Farouk Sabet , Mohamed Elsayed Elshinawi 
 - Cairo :   Mohamed Hosny Abdelnaby Hassan ,   2012 
 - 121 P. :   facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology 
<br/><br/> Cell surface proteases are fund to be associated with caveolae lipid rafts on plasmamembrane of tumor cells . Caveolin - 1 belongs to a family of scaffolding proteins and the P132L point mutation of this gene has been found in up to 16% of all examined breast cancers. Subsequent studies have revealed that the P132L mutation exerts a dominant negative effect through misfolding during cav-1 oligomerization 
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<br/><br/><label>Subjects--Index Terms: </label>Cav-1  Caveolae  CTSB