TY - BOOK AU - Mohamed Hosny Abdelnaby Hassan AU - Mohamed Elsayed Elshinawi , AU - Mona Mostafa Mohamed , AU - Salwa Farouk Sabet , TI - Elucidating the role of caveolae associated proteases in breast cancer Egyptian patients / PY - 2012/// CY - Cairo : PB - Mohamed Hosny Abdelnaby Hassan , KW - Cav-1 KW - Caveolae KW - CTSB N1 - Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Zoology; Issued also as CD N2 - Cell surface proteases are fund to be associated with caveolae lipid rafts on plasmamembrane of tumor cells . Caveolin - 1 belongs to a family of scaffolding proteins and the P132L point mutation of this gene has been found in up to 16% of all examined breast cancers. Subsequent studies have revealed that the P132L mutation exerts a dominant negative effect through misfolding during cav-1 oligomerization ER -