Eman Abdelhamed Aly Nada

Tissue liver x - receptor alpha ( LXRÜ ) level in acne vulgaris / مستوى مستقبلات أنسجة خلايا الكبد اكس الفا فى مرض حب الشباب الشائع Eman Abdelhamed Aly Nada ; Supervised Shereen Osama Tawfic , Marwa Ahmed Ezzat , Olfat Gamil Shaker - Cairo : Eman Abdelhamed Aly Nada , 2012 - 108 P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

Acne vulgaris is a disease of the pilosebaceous unit . Increased sebum lipogenesis by sebaceous gland is the major factor in the pathophysiology of acne . LXRÜ have been recognized in the regulation of genes involved in lipid biosynthesis . Activation of LXRÜ inhibits proliferation , increase lipogenesis and improve differentiation of sebocytes



Acne vulgaris Liver x receptors (LXR) Pathogenesis