Synthesis and characterization of some Azole, Azine and thiophene derivatives /
تحضير و تحديد التركيب البنائي لبعض مشتقات الأزول و الأزين و الثيوفين
Adel Elsayed Hassanine AbouElkhair ; Supervised Rafat Milad Mohareb
- Cairo : Adel Elsayed Hassanine Abouelkhair , 2011
- 160 P. ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Organic Chemistry
Hydrazone group plays an important role for the antimicrobial and antifungal activities. We report in the first part of the original work the synthesis of hydrazide-hydrazone derivatives 3a-c via the reaction of cyanoacetyl-hydrazine 1 with Ü-bromoketones 2a-c. The compounds 3a-c underwent cyclization when heated in sodium ethoxide to form 1,3,4-oxadiazine derivatives