Reham Mostafa Mohamed Rashad Elhazek

Synthesis of some new thiazolo [4,5-b] pyrane derivatives bearing a sulphonamide moiety as potential anticancer agents and radiosensitizers / تحضير بعض مشتقات الثيازولو [ ٤: ٥ - ب ] بيران الجديدة والتى تحتوى على مجموعة السلفوناميد المحتمل لها نشاطا كمضادات للسرطان وكمحفزات للإشعاع Reham Mostafa Mohamed Rashad Elhazek ; Supervised Fatma Abdelfattah Ragab , Helmy Ismail Heiba - Cairo : Reham Mostafa Mohamed Rashad Elhazek , 2012 - 166P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

In the search for new cytotoxic agents with improved anticancer profile some new thiazolo [ 4,5 - b ] pyrane and thiazolo [ 4,5 - b ] pyrano [ 2 , 3 - d ] pyrimidine derivatives bearing a free sulfonamide moiety were synthesized . All the newly synthesized target compounds were subjected to in vitro anticancer screening against human breast cancer cell line (MCF - 7 )



Agents and radiosensitizers New cytotoxic Pyrane and thiazolo