Shaymaa Ahmed Ramadan Ahmed

Effect of sildenafil citrate on rat model of acetic acid induced acute and chronic colitis / دور السيلدينافيل كعامل مؤثر فى التهاب المتلدن (القولون) الكيميائي الحاد و المزمن فى فئران التجارب Shaymaa Ahmed Ramadan ; Supervised Alaa Eldin Afifi , Osama Mohammad Ahmed - Cairo : Shaymaa Ahmed Ramadan Ahmed , 2012 - 122 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Physiology

The results of biochemical, histopathological, oxidative stree and antioxidant defense system markers revealed that acetic acid induced an inflammatory ulcerative colitis indicated by elevated serum TNF-Ü and IL-1Ý. The antioxidant defense system parameters in both colon and rectum tissues (GSH, SOD and Px) are decreased as a result of acetic acid administration



Calmoduline Glutathione peroxidase Tetrahydrobiopterin