TY  - BOOK
AU  - Sherif Mofeed Megalla Ekladious
AU  - Hazem Elsayed Abouyoussef , 
AU  - Marianne Samir Makboul , 
AU  - Sahar Abdelatty Sharaf , 
TI  - Real - time PCR assay of VKORC1 and CYP2C9 gene polymorphisms that affect warfarin response / 
PY  - 2012///
CY  - Cairo : 
PB  - Sherif Mofeed Megalla Ekladious , 
KW  - CYP2C9
KW  - VKORC1
KW  - Warfarin
N1  - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD
N2  - Warfarin is a commonly used oral anticoagulant with a narrow therapeutic index and various genetic and clinical factors that influence interpatient variability in dose requirements . This study investigated the impact of genetic and nongenetic factors on warfarin dose requirements in Egyptians . DNA was extracted from 50 patients taking warfarin for more than 1 year and genotyped for VKORC1 (1173 C> T) , CYP2C9 *3 (1075 C>)gene polymorphisms using SYBR Green - based multiplex allele - specific PCR
ER  -