Osteoprotegerin as a prognostic marker in patients with breast cancer /
دور الاستيوبروتيجرين كدلالة على تطور المرض فى مرضى سرطان الثدى
Radwa Mohammed Gaber ; Supervised Amina Kamal Eldeen Elansary , Samar Ali Marzouk , Ahmed Abdelmabood Zeeneldin
- Cairo : Radwa Mohammed Gaber , 2012
- 122P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry
Bone is a common site for metastasis in breast cancer ; approximately 75 % of women with advanced breast cancer will develop bone metastases . Bone metastases associated with breast cancer are predominately osteolytic . OPG overexpression by breast cancer cells enhances osseous tumor growth . OPG promote tumor cell survival and protect them from TRAIL induced apoptosis