Radwa Mohammed Gaber

Osteoprotegerin as a prognostic marker in patients with breast cancer / دور الاستيوبروتيجرين كدلالة على تطور المرض فى مرضى سرطان الثدى Radwa Mohammed Gaber ; Supervised Amina Kamal Eldeen Elansary , Samar Ali Marzouk , Ahmed Abdelmabood Zeeneldin - Cairo : Radwa Mohammed Gaber , 2012 - 122P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry

Bone is a common site for metastasis in breast cancer ; approximately 75 % of women with advanced breast cancer will develop bone metastases . Bone metastases associated with breast cancer are predominately osteolytic . OPG overexpression by breast cancer cells enhances osseous tumor growth . OPG promote tumor cell survival and protect them from TRAIL induced apoptosis



Bone metastasis Breast cancer OPG