TY - BOOK AU - Radwa Mohammed Gaber AU - Ahmed Abdelmabood Zeeneldin , AU - Amina Kamal Eldeen Elansary , AU - Samar Ali Marzouk , TI - Osteoprotegerin as a prognostic marker in patients with breast cancer / PY - 2012/// CY - Cairo : PB - Radwa Mohammed Gaber , KW - Bone metastasis KW - Breast cancer KW - OPG N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry; Issued also as CD N2 - Bone is a common site for metastasis in breast cancer ; approximately 75 % of women with advanced breast cancer will develop bone metastases . Bone metastases associated with breast cancer are predominately osteolytic . OPG overexpression by breast cancer cells enhances osseous tumor growth . OPG promote tumor cell survival and protect them from TRAIL induced apoptosis ER -