The correlation between hormone receptors, HER 2 and topoisomerase II and response to neoadjuvant chemotherapy in locally advanced breast cancer /
العلاقه بين وجود مستقبلات الهرمون و الهير٢ و التوبوايزوميراز٢ و الاستجابه للعلاج الكيماوى كعلاج أولى فى حالات سرطان الثدى المتقدم
Dalia Hamouda Elsadek Elsaid ; Supervised Nasr M. Ali Ellahloby , Magda Mourad Elsayed , Fouad Mohamed AbouTaleb
- Cairo : Dalia Hamouda Elsadek Elsaid , 2012
- 196 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology-Medical
Topoisomerase II-Ü is a molecular target of anthracyclines; several studies have suggested that topoisomerase II-Ü expression is related to response to anthracycline treatment. The objective of this study was to evaluate correlation between overexpression of Topo II-Ü, HER2-neu, and hormone receptors and response to primary anthracyclin-based chemotherapy in locally advanced breast cancer
Anthracycline Locally advanced breast cancer Topoisomerase II-Ü