Alaa Abdalhamid Mohammed Ali <br/><br/>
The relation between plasma concentration of osteopontin and matrix metalloproteinase-2 and severity of chronic heart failure /  
 العلاقة بينتركيز الأوستيوبونتين و الميتالوبروتينيز-2 فى البلازما و شدة فشل عضلة القلب المزمن 
Alaa Abdalhamid Mohammed Ali ; Supervised Amina Kamal Eldein Elansary , Yaser Ahmed Abdelhady , Salwa Fayez Hasan 
 - Cairo :   Alaa Abdalhamid Mohammed Ali ,   2012 
 - 155 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry 
<br/><br/> Extracellular matrix remodeling is thought to play an important role in the progression of heart failure (HF). Matrix metalloproteinases-2 (MMPs) havebeen demonstrated to influence left ventricular properties and serve as targets of potential anti-remodeling agents. osteopontin, a glycoprotein that can be detected in plasma, was found to be up regulated in several animal models of cardiac failure and may thus represent a new biomarker that facilitates risk stratification in patients with heart failure 
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<br/><br/><label>Subjects--Index Terms: </label>Heart failure Metalloproteinase-2 Osteopontin