TY - BOOK AU - Alaa Abdalhamid Mohammed Ali AU - Amina Kamal Eldein Elansary , AU - Salwa Fayez Hasan , AU - Yaser Ahmed Abdelhady , TI - The relation between plasma concentration of osteopontin and matrix metalloproteinase-2 and severity of chronic heart failure / PY - 2012/// CY - Cairo : PB - Alaa Abdalhamid Mohammed Ali , KW - Heart failure KW - Metalloproteinase-2 KW - Osteopontin N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry; Issued also as CD N2 - Extracellular matrix remodeling is thought to play an important role in the progression of heart failure (HF). Matrix metalloproteinases-2 (MMPs) havebeen demonstrated to influence left ventricular properties and serve as targets of potential anti-remodeling agents. osteopontin, a glycoprotein that can be detected in plasma, was found to be up regulated in several animal models of cardiac failure and may thus represent a new biomarker that facilitates risk stratification in patients with heart failure ER -