Sara Shaban Ibrahim Mohamed <br/><br/>
Synthesis of new thiazole derivatives bearing a sulfonamide moiety of expected anticancer and radiosensitizing activities /  
 تحضير مشتقات الثيازول الجديدة والتى تحتوى على مجموعة السلفوناميد والمتوقع لها نشاطا كمضادات للسرطان وكمحفزات للاشعاع 
Sara Shaban Ibrahim Mohamed ; Supervised Mohamed Abdelrahman Shaaban , Helmy Imail Heiba , Hanan Mohamed Refaat 
 - Cairo :   Sara Shaban Ibrahim Mohamed ,   2012 
 - 123P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Organic Chemistry 
<br/><br/> In a search for new cytotoxic agents with improved antitumor activity and selectivity , some new pyranothiazole and thiazolopyranopyimidine derivatives bearing sulfonamide moiety were synthesized . The newly synthesized compounds were evaluated for their antitumor activity alone and in combination with y - irradiation  . These new compounds were docked inside the active site of carbonic anhydrase II to predict their mechanism of action 
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<br/><br/><label>Subjects--Index Terms: </label>Anticancer Sulfonamide Thiazole