Study of the possible mechanisms of action of atorvastatin in an air - pouch model of inflammation induced in rats /
دراسة الآليات الممكنة لعمل أتورفاستاتين فى نموذج حقيبة الهواء المسببة للالتهاب فى الجرذان
Jamal Mohamed Dammona ; Supervised Hisham Attia Awad , Amani Nabil Shafik , Mostafa Mahmoud Khodeir
- Cairo : Jamal Mohamed Dammona , 2012
- 137P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology
Statins exert favorable effects on lipoprotein metabolism but may also possess anti - inflammatory effects . Several reports have described the ability of statins to suppress acute and chronic inflammations . The aim of this study was to determine the anti - inflammatory effect of atorvastatin in the rat air - pouch model of inflammation and whether its action is on mevalonate pathway , affecting vascular permeability or beta receptors regulation
Anti - inflammatory Atorvastatin Mevalonate pathway