Possible effect of omeprazole , pantoprazole and ranitidine on the antiplatelet activity of clopidogrel in albino rats and mice /
التأثير المحتمل للأوميبرازول والبانتوبرازول والرانيتيدين على وظيفة عقار الكلوبيدوجريل كمضاد للصفائح الدموية فى الفئران والجرذان البيضاء
Mohamed Mahmoud Ahmed Ahmed ; Supervised Ebtissam Abdelghaffar Metwally , Essam Fouad Alalkamy
- Cairo : Mohamed Mahmoud Ahmed Ahmed , 2012
- 101P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pharmacology
Studies have raised concerns that many proton pump inhibitors (PPIs) , especially ompeprazole might diminish the antiplatelet effects and the clinical effectiveness of clopidogrel . By contrast , a preliminary report of data from another trial did find an association between use of a PPI in combination with clopidogrel and an increased risk of adverse outcomes