Synthesis of some new azolo and azine derivatives pendant to pyridine ring with expected biological activity /
تشييد بعض مشتقات أزولو و أزين جديدة متصلة بحلقة البريدين ذات فاعلية بيولوجية متوقعة
Heba Said Abdalghafar ; Supervised Ahmad Mahmoud Farag , Korany Abdallah Khalil
- Cairo : Heba Said Abdalghafar , 2012
- 97 P. : charts ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Science - Department of Organic Chemistry
This work has been carried out to investigate the utility of pyridine-2,6-bis-(2-cyano-N-phenyl-3-oxopropanethioamide) for the synthesis of a variety of a series of new polysubstituted heterocyclic compounds such as thiophenes and 1,3,4-thiadiazoles attached to 2,6-position of pyridine ring. The newly synthesized compounds were evaluated for their in-vitro anticancer activity against human cancer cell lines