Islam Hani Ali Haridi

Synthesis and pharmacological screening of certain indole derivatives / تشييد ومسح أقربازينى لبعض مشتقات الاندول Islam Hani Ali Hardidi ; Supervised Safinaz Elsayed Abbas , Sally Saad Eldin Elnakkady - Cairo : Islam Hani Ali Haridi , 2012 - 117P. : charts ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

A series of 2 - thienyl - 3 - substitued indole derivatives (78-90) were synthesized . Their structures were established on the basis of elemental and spectral (IR , ¹HNMR and Mass spectral data) studies . All the synthesized compounds have been tested for their antitumor activity against brest cancer cell line (MCF-7) using doxorubicin as a standard drug (IC₅₀ =2.97 og/mI)



2-Thienylindole Anti - inflammatory Antitumor