TY - BOOK AU - Amjad Ghassan AbuAlfadel AU - Manal Mohamed Hosny Mostafa , AU - Weam Rashwan , TI - Matrix metalloproteinase -13 (MMP-13) level in gingival crevicular fluid (GCF) of chronic periodontitis patients before and after periodontal therapy / PY - 2012/// CY - Cairo : PB - Amjad Ghassan AbuAlfadel , KW - Chronic periodontitis KW - MMP-13 KW - MMPs N1 - Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology; Issued also as CD N2 - MMP-13 has been shown to be expressed by periodontitis affected human gingival sulcular epithelium and gingival fibroblasts. Several studies have demonstrated elevated MMP-13 levels in GCF and diseased gingival tissues in chronic periodontitis patients. In addition, increased MMP-13 activity during disease activity has been reported suggesting a role for MMP-13 in periodontal tissue destruction and/or alveolar bone loss ER -