TY - BOOK AU - Hoda Abdallah Abdelfatah AU - Eman Abdelmohsen Shaheen , AU - Mona Hassan Eltagui , AU - Mona Mohamed Hamdy , TI - Apolipoprotien €4 allele as a genetic risk factor for left ventricular failure in Ý - thalassemia major / PY - 2012/// CY - Cairo : PB - Hoda Abdallah Abdelfatah , KW - Apolipoprotien E4 KW - Hart failure KW - Ý-thalassemia major N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD N2 - Heart failure is the main cause of death in Ý thalassemia major patients , which is mainly attributed to iron overload through the formation of oxygen free radicals . Apolipoprotein epsilon 4 (ApoE4) allele has the least antioxidant activity compared to ApoE3 alleles . This study was designed to determine whether the ApoE4 allele could represent a genetic rick factor for the development of left ventricular failure in Ý thalassemia major UR - http://172.23.153.220/th.pdf ER -