TY - BOOK AU - Yasmin Saied Aly AU - Hafez Mahmoud Bazaraa , AU - Hanaa Ibrahim Rady , AU - Mona Hassan Hafez , TI - Adrenocortical status in infants and children with sepsis and septic shock / PY - 2012/// CY - Cairo : PB - Yasmin Saied Aly , KW - Corticosteroids KW - Pediatric ICU KW - Relative adrenal insufficiency N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics; Issued also as CD N2 - Servere sepsis and septic shock remain a major cause of morbidity and mortality in Paediatric ICU . Whether these patiients would benefit from corticosteroids remains controversial and the presence of adrenocortical insufficiency has been proposed to justify steroid use . In order to study adrenocortical state in infants and children with SIRS and septic shock , cortisol levels were estimated at baseline and after high - dose ACTH stimulation in 30 cases and 30 controls ER -