Hesham Adel Saleh <br/><br/>
Isolation, purification and biological evaluation of sarcophine and one of its semisynthetic derivatives from the Red Sea soft coral Sarcophyton glaucum /  
Hesham Adel Saleh ; Supervised Nazih Noureldin , Hans-Georg Breitinger 
 - Cairo :   Hesham Adel Saleh ,   2010 
 - 98Leaves :   charts ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry 
<br/><br/> Sarcophine is an epoxy cembranolide isolated in good yields from the Red Sea soft coral Sarcophyton glaucum showing various biological activities ; most prominent are its anticancer effects . However since the molecule is primarily a defense toxin for its coral ; utilizing this lead compound for pharmacological use is conditioned by its toxicity profile that would hinder introducing it for clinical trials if not safe levels