TY - BOOK AU - Hesham Adel Saleh AU - Hans-Georg Breitinger , AU - Nazih Noureldin , TI - Isolation, purification and biological evaluation of sarcophine and one of its semisynthetic derivatives from the Red Sea soft coral Sarcophyton glaucum / PY - 2010/// CY - Cairo : PB - Hesham Adel Saleh , N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry N2 - Sarcophine is an epoxy cembranolide isolated in good yields from the Red Sea soft coral Sarcophyton glaucum showing various biological activities ; most prominent are its anticancer effects . However since the molecule is primarily a defense toxin for its coral ; utilizing this lead compound for pharmacological use is conditioned by its toxicity profile that would hinder introducing it for clinical trials if not safe levels ER -