Amal Mahmoud Yassin Mohsen <br/><br/>
Synthesis and pharmacological evaluation of 1-Benzyl and 1-Benzoyl melatonin analogs as ligands for melatonin receptors /  
 تشييد وتقييم بيولوجى ل ن 1 بنزايل و ن 1 بنزويل من مشتقات الميلاتونين كلجائن لمستقبلات الميلاتونين 
Amal Mahmoud Yassin Mohsen ; Supervised Darius P. Zlotos 
 - Cairo :   Amal Mahmoud Yassin Mohsen ,   2010 
 - 84Leaves :   charts , facsimiles ;   30cm 
<br/><br/>Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry 
<br/><br/> The neurohormone melatonin (MLT) exerts its diverse physiological actions mostly through activation of the two G-protein-coupled MT₁ and MT₂ receptors . An accurate characterization of MLT receptor-mediated functions requires MT₁ and MT₂ selective ligands . One of the most selective MT₂ antagonists up to date is the p - chlorobenzl substituted indole derivative UCM 454