TY - BOOK AU - Salma Nabil Tammam AU - Nagia Nagib Afifi , AU - Ola Heikal , TI - Application of biodegradable nanopartieles in liver targeting of tacrolimus / PY - 2010/// CY - Cairo : PB - Salma Nabil Tammam , N1 - Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Technology N2 - Tacrolimus is a potent immunosuppressant used in liver transplantation to avoid graft rejection. Tacrolimus has a narrow therapeutic index and exhibits variable phamacokinetics with high inter and intra-patient variability making dose adjustment and therapeutic drug monitoring a complicated task, not to mention increasing the occurrence of adverse effects UR - http://172.23.153.220/th.pdf ER -