Safa Nabil Abdelfattah Mohamed <br/><br/>
Mdm2 and p53 codon 72 polymorphisms in acute myeloid leukemia /  
 فى حالات سرطان الدم الميلودى الحادP53 وشفرة 72 للجينMDM2 المظاهرة المتعددة للجين 
Safa Nabil Abdelfattah Mohamed ; Supervised Nabil Mohsen Eldanasouri , Shadia Hassan Ragab , Zainab Ali Hassan Elsaadany 
 - Cairo :   Safa Nabil Abdelfattah Mohamed ,   2012 
 - 200P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology 
<br/><br/> Acute myeloid leukemia (AML) is a heterogeneous disease with numerous genetic abnormalities . Among them , functional SNPs in both , the tumor suppressor protein , p53 and its key cellular regulator Mdm2 . We investigated the risk of Mdm 2 SNP309 alone or in combination with the p53 codon 72 polymorphism in AML patients in a study that included 50 de novo AML patients and 50 healthy control subjects 
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<br/><br/><label>Subjects--Index Terms: </label>Acute myeloid leukemia  Mdm2  P53