TY - BOOK AU - Safa Nabil Abdelfattah Mohamed AU - Nabil Mohsen Eldanasouri , AU - Shadia Hassan Ragab , AU - Zainab Ali Hassan Elsaadany , TI - Mdm2 and p53 codon 72 polymorphisms in acute myeloid leukemia / PY - 2012/// CY - Cairo : PB - Safa Nabil Abdelfattah Mohamed , KW - Acute myeloid leukemia KW - Mdm2 KW - P53 N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD N2 - Acute myeloid leukemia (AML) is a heterogeneous disease with numerous genetic abnormalities . Among them , functional SNPs in both , the tumor suppressor protein , p53 and its key cellular regulator Mdm2 . We investigated the risk of Mdm 2 SNP309 alone or in combination with the p53 codon 72 polymorphism in AML patients in a study that included 50 de novo AML patients and 50 healthy control subjects UR - http://172.23.153.220/th.pdf ER -