Modulation of endotoxin-induced cardiac stress in rats /
تعديل الاجهاد القلبى المحدث بالذيقان الداخلى فى الجرذان
Azza Mohamed Abdeltawab Yehia ; Supervised Tarek M. Kamal Motawi , Hebatallah Abdelmoeti Mohamed
- Cairo : Azza Mohamed Abdeltawab Yehia , 2012
- 164P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Biochemistry
Endotoxin (lipopolysaccharides ; LPS) are known to cause multiple organ failure , including myocardial dysfunction . The present study investigated the effect of pentoxifylline (PTX) , a tumor necrosis factor alpha (TNF-Ü) inhibitor , aminoguanidine (AG) , a selective inducible nitric oxide synthase (iNOS) inhibitor and caffeic acid phenethyl ester (CAPE) , a natural antioxidant , on endotoxin - induced cardiac stress