Walaa Ibrahim Ali Ahmed <br/><br/>
Effect of mesenchymal stem cells and a cureumin derivative on notch signaling in hepatocellular carcinoma /  
 تأثير الخلايا الجذعية و مشتق من الكوركومين على إشارات نوتش فى سرطان الكبد 
Walaa Ibrahim Ali Ahmed ; Supervised Hussein Mostafa Khaled , Nagwa Kamal Eldin Roshdy , Ali Alhendawy 
 - Cairo :   Walaa Ibrahim Ali Ahmed ,   2013 
 - 221 P. :   charts ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Medical Biochemistry 
<br/><br/> In some human cancers, the Notchl receptor and signaling pathway is upregulated, which increases the oncogenic potential of the cell through prevention of differentiation and inhibition of apoptosis. So, from this aspect we evaluated the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on hepatocellular carcinoma (HCC) both in vivo in hepatoma induced animal model in rats and in vitro on HepG2 cells (hepatoma cell line) 
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<br/><br/><label>Subjects--Index Terms: </label>Hepatocellular carcinoma MSCs Notch signaling