Mohamad Saeed Marie <br/><br/>
Interleukin - 28B gene polymorphism in Egyptian patients with chronic hepatitis C infection related liver diseases /  
 تعددية الأشكال لجين الأنترلوكين ٢٨ب فى المرضى المصريين المصابين بأمراض الكبد الناتجه عن الألتهاب الكبدى المزمن بفيروس ج 
Mohamad Saeed Marie ; Supervised Hosny Mohamad Salama , Eman Medhat Hassan , Abdelrahman Zekri 
 - Cairo :   Mohamad Saeed Marie ,   2012 
 - 139P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine 
<br/><br/> Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection . Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV - induced disease in the clinical course from mild chronic hepatitis C to hepatocellular carcinoma . We have determined the rs12979860 single nucleotide polymorphism ( SNP ) upstream IL28B gene in three groups of Egyptian patients with HCV - induced chronic liver disease : 1 ) 119 patients with biopsy - proven chronic hepatitis C , to analyze its relation with biochemical and histological features  
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<br/><br/><label>Subjects--Index Terms: </label>Arcinoma in the Egyptian patients  HCV  SNP