TY - BOOK AU - Mohamad Saeed Marie AU - Abdelrahman Zekri , AU - Eman Medhat Hassan , AU - Hosny Mohamad Salama , TI - Interleukin - 28B gene polymorphism in Egyptian patients with chronic hepatitis C infection related liver diseases / PY - 2012/// CY - Cairo : PB - Mohamad Saeed Marie , KW - Arcinoma in the Egyptian patients KW - HCV KW - SNP N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine; Issued also as CD N2 - Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection . Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV - induced disease in the clinical course from mild chronic hepatitis C to hepatocellular carcinoma . We have determined the rs12979860 single nucleotide polymorphism ( SNP ) upstream IL28B gene in three groups of Egyptian patients with HCV - induced chronic liver disease : 1 ) 119 patients with biopsy - proven chronic hepatitis C , to analyze its relation with biochemical and histological features UR - http://172.23.153.220/th.pdf ER -