Abdalaziz Mostafa Abdalziz Zahran  <br/><br/>
The effect of low - dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock /  
 تأثير الجرعات المنخفضة من عقار الهيدروكورتيزون على جرعات النورابينفرين ونسبة اللاكتات بالدم فى مرضى الصدمة البكتيرية الغير مستجيبة للعلاج التقليدى 
Abdalaziz Mostafa Abdalziz Zahran ; Supervised Hesham Alaassar , Sameh Elmaraghi , Ayman Heikal 
 - Cairo :   Abdalaziz Mostafa Abdalziz Zahran ,   2012 
 - 154P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine 
<br/><br/> Cortisol is necessary to survive critical but absolute adrenal insufficiency is rare among critically ill patients . However many observations argue that suboptimal cortisol production may be common and associated with worse outcomes . Suboptimal cortisol production during septic shock has been termed functional or relative adrenal insufficiency . In the 1990 s interest in corticosteroids as a therapy in septic shock was renewed this time using smaller more physiological doses for longer duration 
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<br/><br/><label>Subjects--Index Terms: </label>Hydrocortisone  Refractory septic shock  Serum lactate