Rana Ahmed Abdelfattah

Assoiation of vascular endothelial growth factor gene polymorphism with diabetic retinopathy in type 2 diabetes mellitus in Egyptian patients / العلاقة بين تعدد الشكل الجينى لعامل نمو بطانة الاوعية الدموية واعتلال الشبكية السكرى فى مرضى السكر من النوع الثانى فى المصريين Rana Ahmed Abdelfattah ; Supervised Mostafa Hamed Nabih , Rasha Mounir Abdelkader , Manal Mohammed Kamal - Cairo : Rana Ahmed Abdelfattah , 2013 - 79 P. : charts , facsimiles ; 25cm

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Ophthalmology

VEGF has been implicated as major contributor to the development of DR . Several SNPs have been thought to be associated with differential expression of VEGF . We aimed at investigating whether rs699947 , rs10434 SNPs of VEGF gene are associated to DR in an Egptian cohort of patients with type 2 DM . There was no statistically significant association between the studied SNPs and DR . There are conflicting results in different populations which may be due to gene - gene interaction or gene - environmental interaction



Confidence interval Endothelial cells Interleukin - 1Ý