Noha Tarek Moharned Elhusseiny Esh <br/><br/>
Impact of circulating erythrocyte - derived microparticles on coagulation activation in sickle cell disease /  
 تأثير الجزيئات الدقيقة المشتقة من كرات الدم الحمراء على نشاط التجلط فى مرض أنيميا الخلايا المنجلية  
Noha Tarek Moharned Elhusseiny Esh ; Supervised Rania Ahmed Zayed , Mona Kamal Elghamrawy , Hanan Alhusseini Mohamed 
 - Cairo :   Noha Tarek Moharned Elhusseiny Esh ,   2013 
 - 130P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology 
<br/><br/> Background: Sickle cell disease (SCD) is characterized by a hypercoagulable state as a result of multiple factors including chronic hemolysis and the presence of circulating cell- derived microparticles (MPs) . The cellular origin of such MPs and the exact mechanism by which it enhance coagulation in SCD are not fully understood . The study aimed to clarify the presence of circulating erythrocyte - derived MPs in SCD patients during painful crisis and in steady state and the impact of these MPs on coagulation activation and fibrinolysis 
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<br/><br/><label>Subjects--Index Terms: </label>Coagulation activation D-dimer   Erythrocyte - derived microparticles