TY - BOOK AU - Asmaa Esmail Ali AU - Dina Ahmed Mehaney , AU - Hazem Elsayed Aboyoussef , AU - Manal Mohamed Kamal , TI - Validation of triple marker medians used in antenatal screening of Egyptian females / PY - 2013/// CY - Cairo : PB - Asmaa Esmail Ali , KW - Down syndrome KW - Other fetal aneuploidy KW - Triple test screening N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD N2 - Background and aim of work : Down syndrome(DS) is the most commonly recognized genetic cause of mental retardation . The risk of DS is directly related to maternal age . Women younger than 35 years should be offered maternal serum screening at 16 to 18 weeks of gestation . The maternal serum markers used to screen for DS are alpha- fetoprotein (AFP) unconjugated estriol (uE3)and human chorionic gonadotrophin (hCG) UR - http://172.23.153.220/th.pdf ER -