Effect of mefloquine in murine schistosomiasis mansoni as a prophylactic and chemotherapeutic agent compared to praziquantel /
تأثير المفلوكين على البلهارسيا المعوية فى الفئران كعامل وقائى وعلاجى مقارنة بالبرازيكوانتال
Shaimaa Helmy Elsayed Ismail ; Supervised Maisa Mohamed Kamel , Soaad Ismail Hassan , Nagwa Abdelkhalek Talaat Elkhafif
- Cairo : Shaimaa Helmy Elsayed Ismail , 2013
- 148 P. : charts , facsimiles , maps ; 25CM
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology
Schistosomiasis is a chronic debilitating disease that continues to threaten millions of people, and to be the 2nd major parasitic disease worldwide after malaria in term of morbidity, mortality, and prevalence . The treatment and control of human schistosomiasis rely on a single drug, praziquantel (PZQ), that effectively kills adult schistosomes but lacks efficacy against schistosomulae (juvenile schistosomes) a fact that explains low observed cure rates of schistosomiasis