TY - BOOK AU - Shaimaa Helmy Elsayed Ismail AU - Maisa Mohamed Kamel , AU - Nagwa Abdelkhalek Talaat Elkhafif , AU - Soaad Ismail Hassan , TI - Effect of mefloquine in murine schistosomiasis mansoni as a prophylactic and chemotherapeutic agent compared to praziquantel / PY - 2013/// CY - Cairo : PB - Shaimaa Helmy Elsayed Ismail , KW - MFQ KW - PZQ KW - Schistosomiasis mansoni N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Parasitology; Issued also as CD N2 - Schistosomiasis is a chronic debilitating disease that continues to threaten millions of people, and to be the 2nd major parasitic disease worldwide after malaria in term of morbidity, mortality, and prevalence . The treatment and control of human schistosomiasis rely on a single drug, praziquantel (PZQ), that effectively kills adult schistosomes but lacks efficacy against schistosomulae (juvenile schistosomes) a fact that explains low observed cure rates of schistosomiasis ER -