Leptin in sepsis : A well suited biomarker in critically ill patients /
الليبتن فى مرض تعفن الدم : كمؤشر جديد فى التشخيص المبكر وقدرتة على التنبؤ بمستقبل الحالات الحرجة
Noura Ahmed Abdelhameed Farg ; Supervised Gamal Hamed , Enas Abdellatiff , Khaled M. Taema
- Cairo : Noura Ahmed Abdelhameed Farg , 2013
- 144 P. : charts , facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine
Sepsis with acute organ dysfunction (severe sepsis) is common and frequentry fatal. Leptin, a hormone mainly generated by adipocyctes, has several activating effects towards T cells, monocytes, endothelium cells and cytokine production suggesting a protective role of leptin in the setting of an acute systemic inflammation serum leptin level on 2nd day can differentiate between sepsis and noninfectious SIRS and its level of 38.05ægm/L has a sensitivity of 93% and a specificity of 100% to diagnose sepsis