TY - BOOK AU - Noura Ahmed Abdelhameed Farg AU - Enas Abdellatiff , AU - Gamal Hamed , AU - Khaled M. Taema , TI - Leptin in sepsis : : A well suited biomarker in critically ill patients / PY - 2013/// CY - Cairo : PB - Noura Ahmed Abdelhameed Farg , KW - Leptin KW - Sepsis KW - Serum leptin level N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine; Issued also as CD N2 - Sepsis with acute organ dysfunction (severe sepsis) is common and frequentry fatal. Leptin, a hormone mainly generated by adipocyctes, has several activating effects towards T cells, monocytes, endothelium cells and cytokine production suggesting a protective role of leptin in the setting of an acute systemic inflammation serum leptin level on 2nd day can differentiate between sepsis and noninfectious SIRS and its level of 38.05ægm/L has a sensitivity of 93% and a specificity of 100% to diagnose sepsis ER -