Synthesis and biological evaluation of a novel series of chalcones as antimicrobial and / or anticancer agents /
التحضير و التقييم البيولوجى لسلسلة جديده من الشالكونات كمضادات للميكروبات و / أو مضادات للسرطان
Magda Fikry Mahmoud Mohamed ; Supervised Mohamed Mohamed Fathi , Samia Shouman , Mervat Elsayed Mohamed
- Cairo : Magda Fikry Mahmoud Mohamed , 2013
- 152 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Biochemistry
A newly synthesized series of chalcone derivatives containing pyrazole rings were synthesized and evaluated for their cytotoxic activities in vitro against several human cancer cell lines. The prepared compounds showed potential cytotoxicity against human cancer cell lines MCF-7, HEPG-2 and HCT-116. Also the compounds were evaluated as antimicrobial agents
Cancer cell lines-MCF-7, HEPG-2 and HCT-116 Chalcones Potential pharmacological activity