TY - BOOK AU - Rania Mohamed Rahmo AU - Dalaal Moustafa Abdallah , AU - Laila Gamal Mahran , AU - Sanaa Abdelbaky Kenawy , TI - Pharmacological study of the possible antiulcerogenic effect of certain natural substances extracted from different medicinal plants / PY - 2013/// CY - Cairo : PB - Rania Mohamed Fouad Rahmo , KW - Indomethacin KW - Peptic ulcer KW - Reactive oxygen species N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology; Issued also as CD N2 - A major clinical problem encountered with the use of indomethacin (IMN),a Non-steroidal anti-inflammatory drug, is gastrointestinal complications. It was reported that IMN develops gastropathy by inducing reactive oxygen species(ROS)as well as pro-inflammatory mediators such as tumor necrosis factor Ü (TNF-Ü). Moreover, IMN induced peptic ulcer (PU) by inducing apoptotic death, manifested by an increase in the expression of Cyt c and caspase-3 UR - http://172.23.153.220/th.pdf ER -