Enas Hassan Elsayed

Evaluation of hypermethylated rassfia gene as a molecular marker for diagnosis of hepatocellular carcinoma / الميثيلى كدلالة لتشخيص سرطان الكبد الخلوى RASSF1تقييم جين Enas Hassan Elsayed ; Supervised Lamiaa Aly Mansour , Maysa Elsayed Elrazky , Aml Abdelwahab Mohamed - Cairo : Enas Hassan Elsayed , 2013 - 136 Leaves : charts , facsimiles ; 30cm

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Inactivation of the tumor suppressor gene RASSF1 by promoter hypermethylation of CPG islands was frequently encountered in multiple tumors including HCC .Our study investigated the presence of hypermethylation RASSF1A in sera of HCC patients HCV chronic carriers and normal healthy individuals (using the methylation sensitive restriction enzyme mediated real time PCR technique)



Epigenitics Hypermethylation RASSF1A