The prognostic significance of the progenitor cell markers CD34 and CD38 in acute myeloid leukemia /
الدور التشخيصى لمجموعة التمايز 34و38 فى متابعة تطور المرض فى حالات سرطان الدم الميلودى الحاد
Samar Sami Elshazli ; Supervised Menat Allah Kamal Eldin M. , Eman Kamal Abdelfatah , Naglaa Moustafa Hassan
- Cairo : Samar Sami Elshazli , 2013
- In various Paging : facsimiles ; 25cm
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized by the accumulation of acquired genetic alterations in the hematopoietic progenitor cells. The CD34 protein is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic cells. CD38 has multiple biochemical and biological functions and mostly expressed on the surface of immature cells