Mervat Mahmoud Mostafa Eissa <br/><br/>
Serum selerostin level among Egyptian rheumatoid arthritis patients :   Relation to bone mineral density, disease activity and radiological grading /  
 دراسة عن مستوى السكليروستين بمرضى الروماتويد المصريين و علاقته بكثافة العظام و نشاط المرض و الأشعة 
Mervat Mahmoud Mostafa Eissa ; Supervised Somaya Anwar Hussein , Sahar Fakhr Eldin Mohamed , Dina Ahmed Mehaney 
 - Cairo :   Mervat Mahmoud Mostafa Eissa ,   2013 
 - 236 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation 
<br/><br/> Bone loss in rheumatoid arthritis (RA) is caused by increased bone resorption, however, there is no increased bone formation. The Wnt pathway is important in the control of bone formation through regulation of osteoblast activity. Selerostin is an important regulator of regulation of osteoblast activity. Selerostin is an important regulator of the Wnt pathway by blocking Wnt binding to its receptor and therapy inhibiting bone formation 
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<br/><br/><label>Subjects--Index Terms: </label>Bone mineral density Rheumatoid arthritis Selerostin