TY - BOOK AU - Mervat Mahmoud Mostafa Eissa AU - Dina Ahmed Mehaney , AU - Sahar Fakhr Eldin Mohamed , AU - Somaya Anwar Hussein , TI - Serum selerostin level among Egyptian rheumatoid arthritis patients : : Relation to bone mineral density, disease activity and radiological grading / PY - 2013/// CY - Cairo : PB - Mervat Mahmoud Mostafa Eissa , KW - Bone mineral density KW - Rheumatoid arthritis KW - Selerostin N1 - Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Rheumatology and Rehabilitation; Issued also as CD N2 - Bone loss in rheumatoid arthritis (RA) is caused by increased bone resorption, however, there is no increased bone formation. The Wnt pathway is important in the control of bone formation through regulation of osteoblast activity. Selerostin is an important regulator of regulation of osteoblast activity. Selerostin is an important regulator of the Wnt pathway by blocking Wnt binding to its receptor and therapy inhibiting bone formation ER -