Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology
In acute myloid leukemia (AML), both cytogenetic and molecular abnrmalities are strongly assosiated with prognosis. In particular, in cytogenetically normal AML. Families of myeloproliferaive neoplasms (MPNs) are characterized by a clinical and genetic heterogenceity. First, within MPN families, distinct clinical entities are observed, the 3 main ones being polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PME)