Reham Abdelmonem Mohammed <br/><br/>
Genetic profile of self renewal genes in cancer stem cells of human bladder carcinoma /  
 دراسة التحليل الجينى لسرطان الخلايا الجذعية فى المرضى المصابين بسرطان المثانة البولية 
Reham Abdelmonem Mohammed ; Supervised Shereen Mahmoud , Safa Misheel , Husni Khairy 
 - Cairo :   Reham Abdelmonem Mohammed ,   2012 
 - 137 P. :   charts , facsimiles ;   25cm 
<br/><br/>Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology 
<br/><br/> OCT-4 (also known as POU5FI) and BMI-1 (a member of PRCI) are the key regulators of self-renewal in embryonic stem cells. Regarding the new cancer stem cell concept, the expression of such genes are potentially correlated with tumorigenesis and can affect some aspects of tumor behavior, such as tumor recurrence or resistance to therapies. Although OCT--4 and BMI gene expression has been introduced as a molecular marker for germ cell tumors 
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<br/><br/><label>Subjects--Index Terms: </label>Acute myeloid leukemia Fetal calf serum Heamatopoietic stem cell