TY - BOOK AU - Reham Abdelmonem Mohammed AU - Husni Khairy , AU - Safa Misheel , AU - Shereen Mahmoud , TI - Genetic profile of self renewal genes in cancer stem cells of human bladder carcinoma / PY - 2012/// CY - Cairo : PB - Reham Abdelmonem Mohammed , KW - Acute myeloid leukemia KW - Fetal calf serum KW - Heamatopoietic stem cell N1 - Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology; Issued also as CD N2 - OCT-4 (also known as POU5FI) and BMI-1 (a member of PRCI) are the key regulators of self-renewal in embryonic stem cells. Regarding the new cancer stem cell concept, the expression of such genes are potentially correlated with tumorigenesis and can affect some aspects of tumor behavior, such as tumor recurrence or resistance to therapies. Although OCT--4 and BMI gene expression has been introduced as a molecular marker for germ cell tumors UR - http://172.23.153.220/th.pdf ER -