Role of XPD and XRCC1 DNA repair genes single nucleotide polymorphisms in the pathogenesis and outcome of acute myeloid leukemia /
دور الاختلاف أحادى القاعدة لجينات إصلاح الحمض النووى (إكس بى دى وإكس ار سى سى 1) فى كيفية حدوث والمردود العلاجى لمرضى اللوكيميا الميلودية الحادة
Hany Yousry Nasrallah ; Supervised Khaled M. Aboulenein , Basma M. Elgamal , Amany M. Helal
- Cairo : Hany Yousry Nasrallah , 2013
- 124 P. : charts , facsimiles ; 25cm
Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology
Acute myeloblastic leukemia (AML) is a clonal disorder characterized by acquisition of somatic mutations . Despite recent scientific advances in understanding the miolecular biology of AML and mechanisms of multidrug resistance (MDR) yet among adults with AML 5 years survival rate is less than 20%