TY - BOOK AU - Gehan Sobhy Georgy AU - Dalaal Mostafa Abdallah , AU - Hanaa Abdelfattah Mansour , AU - Noha Nagah Nassar , TI - Study of the possible protective effects of an N-methyl-D- aspartate antagonist and a peptide like drug against streptozotocin induced neurodegeneration / PY - 2013/// CY - Cairo : PB - Gehan Sobhy Georgy , KW - Cerebrolysin KW - Memantine KW - Streptozotocin N1 - Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology; Issued also as CD N2 - Cognitive decline, as well as increased dementia is strongly linked to diabetes. Diabetes- associated cognitive decline is accompanied by structural and neurochemical abnormalities, as well as by degenerative chenges in the brain that correlates with chronically increased intracellular glucose concentration. Cerebrolysin (CBL), a mixture of several active peptide fragments and neurotrophic factors including brain-derived neurotrophic factor (BDNF), is used in the management of cognitive alterations in demented patients UR - http://172.23.153.220/th.pdf ER -