Samir Ahmed Shawky

DNA methylation status of dapk and MT1G genes in diffuse large B-cell lympihoma and its clinical relevance / دراسة نسق إضافة مركب الميثيل إلى الحامض النووى الديؤكسى ريبوزى فى الجينين (دى أ بى كا) و (م ت ١ جى) فى حالات سرطان الجهاز الليمفاوى (بى) ذو الخلايا الكبيرة و أهميته الأكلينيكية Samir Ahmed Shawky ; Supervised Mohamed H. Elborai , Hussein M. Khaled , Abeer Ahmad Bahnassy - Cairo : Samir Ahmed Shawky , 2012 - 103 P. : charts ; 30cm

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Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology-Pathology

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of of Non-hodgkin's lymphoma (NHL) and can be divided into prognostically important subgroups with germinal center B-cell-like (GCB) and non-GCB subtypes either by using cDNA microarray or immunostains (CD10, BCL6, MUM1). Beyond genetic alterations, identification of novel epigenetic alterations, such as aberrant methylation may yield better diagnostic, prognostic and therapeutic information

DAPK MT1G Promotor hypermethylation